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ppp2r2a  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology ppp2r2a
    Ppp2r2a, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 37 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ppp2r2a/product/Santa Cruz Biotechnology
    Average 92 stars, based on 37 article reviews
    ppp2r2a - by Bioz Stars, 2026-06
    92/100 stars

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    Santa Cruz Biotechnology anti ppp2r2a
    Silencing of TRPV2 inhibits myocardial apoptosis in MI/RI rats through the Ca 2+ <t>/calcineurin/NFAT</t> axis. a , b TUNEL-positive cells in rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as measured via TUNEL assay. Scale bar = 100 μm. c Ca 2+ concentrations determined using a calcium assay kit. d Protein levels of TRPV2, Bcl‑2, Bax, Survivin, Cleaved Caspase‑3, Calcineurin, and NFAT in MI/RI rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as determined via western blot. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. sham; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. I/R + control adv; ampersand: p < 0.05, double ampersand: p < 0.01, triple ampersand: p < 0.001, quadruple ampersand: p < 0.0001 vs. I/R + NC adv
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    Cell Signaling Technology Inc pp2r2a antibody
    Silencing of TRPV2 inhibits myocardial apoptosis in MI/RI rats through the Ca 2+ <t>/calcineurin/NFAT</t> axis. a , b TUNEL-positive cells in rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as measured via TUNEL assay. Scale bar = 100 μm. c Ca 2+ concentrations determined using a calcium assay kit. d Protein levels of TRPV2, Bcl‑2, Bax, Survivin, Cleaved Caspase‑3, Calcineurin, and NFAT in MI/RI rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as determined via western blot. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. sham; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. I/R + control adv; ampersand: p < 0.05, double ampersand: p < 0.01, triple ampersand: p < 0.001, quadruple ampersand: p < 0.0001 vs. I/R + NC adv
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    Image Search Results


    Silencing of TRPV2 inhibits myocardial apoptosis in MI/RI rats through the Ca 2+ /calcineurin/NFAT axis. a , b TUNEL-positive cells in rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as measured via TUNEL assay. Scale bar = 100 μm. c Ca 2+ concentrations determined using a calcium assay kit. d Protein levels of TRPV2, Bcl‑2, Bax, Survivin, Cleaved Caspase‑3, Calcineurin, and NFAT in MI/RI rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as determined via western blot. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. sham; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. I/R + control adv; ampersand: p < 0.05, double ampersand: p < 0.01, triple ampersand: p < 0.001, quadruple ampersand: p < 0.0001 vs. I/R + NC adv

    Journal: Herz

    Article Title: Tetrandrine has protective role in myocardial ischemia/reperfusion injury via the TRPV2/Ca 2+ /calcineurin/NFAT axis

    doi: 10.1007/s00059-025-05334-w

    Figure Lengend Snippet: Silencing of TRPV2 inhibits myocardial apoptosis in MI/RI rats through the Ca 2+ /calcineurin/NFAT axis. a , b TUNEL-positive cells in rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as measured via TUNEL assay. Scale bar = 100 μm. c Ca 2+ concentrations determined using a calcium assay kit. d Protein levels of TRPV2, Bcl‑2, Bax, Survivin, Cleaved Caspase‑3, Calcineurin, and NFAT in MI/RI rats injected with NC adv/shTRPV2 adv or control adv/TRPV2 adv as determined via western blot. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. sham; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. I/R + control adv; ampersand: p < 0.05, double ampersand: p < 0.01, triple ampersand: p < 0.001, quadruple ampersand: p < 0.0001 vs. I/R + NC adv

    Article Snippet: Calcineurin , 16569-1-AP , 1:1000 , Proteintech, Wuhan, China.

    Techniques: TUNEL Assay, Injection, Control, Calcium Assay, Western Blot

    TET downregulates TRPV2 expression and inhibits the Ca 2+ /calcineurin/NFAT pathway. a mRNA expression and b protein levels of TRPV2, calcineurin, and NFAT in H/R-challenged H9c2 cells after treatment with different concentrations (0.5, 1.0, and 1.5 μM) of TET as measured by qRT-PCR and western blot, respectively. c, d ROS amounts in H/R-challenged H9c2 cells after treatment with different concentrations (0.5, 1.0, and 1.5 μM) of TET as calculated by DCFH-DA staining. Scale bar = 100 μm. e Ca 2+ concentrations in H/R-challenged H9c2 cells treated with different concentrations (0.5, 1.0, and 1.5 μM) of TET as determined using a calcium assay kit. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. control; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. H/R

    Journal: Herz

    Article Title: Tetrandrine has protective role in myocardial ischemia/reperfusion injury via the TRPV2/Ca 2+ /calcineurin/NFAT axis

    doi: 10.1007/s00059-025-05334-w

    Figure Lengend Snippet: TET downregulates TRPV2 expression and inhibits the Ca 2+ /calcineurin/NFAT pathway. a mRNA expression and b protein levels of TRPV2, calcineurin, and NFAT in H/R-challenged H9c2 cells after treatment with different concentrations (0.5, 1.0, and 1.5 μM) of TET as measured by qRT-PCR and western blot, respectively. c, d ROS amounts in H/R-challenged H9c2 cells after treatment with different concentrations (0.5, 1.0, and 1.5 μM) of TET as calculated by DCFH-DA staining. Scale bar = 100 μm. e Ca 2+ concentrations in H/R-challenged H9c2 cells treated with different concentrations (0.5, 1.0, and 1.5 μM) of TET as determined using a calcium assay kit. Double asterisk: p < 0.01, triple asterisk: p < 0.001, quadruple asterisk: p < 0.0001 vs. control; diamond: p < 0.05, double diamond: p < 0.01, triple diamond: p < 0.001, quadruple diamond: p < 0.0001 vs. H/R

    Article Snippet: Calcineurin , 16569-1-AP , 1:1000 , Proteintech, Wuhan, China.

    Techniques: Expressing, Quantitative RT-PCR, Western Blot, Staining, Calcium Assay, Control